Publications
Salvinorin A and related compounds as therapeutic drugs for psychostimulant-related disorders
Salvinorin A is a κ-opioid receptor agonist extracted from Salvia divinorum. It has demonstrated anti-addiction effects in animal models using psychostimulants by attenuating dopamine release, sensitization, and other neurochemical and behavioral alterations associated with acute and prolonged use of certain drugs.
Salvinorin A is a κ-opioid receptor agonist extracted from Salvia divinorum. It has demonstrated anti-addiction effects in animal models using psychostimulants by attenuating dopamine release, sensitization, and other neurochemical and behavioral alterations associated with acute and prolonged use of certain drugs.
The effectiveness and risks of long-term opioid therapy for chronic pain: A systematic review for a national institutes of health pathways to prevention workshop
Increases in prescriptions of opioid medications for chronic pain have been accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty about long-term effectiveness.
Increases in prescriptions of opioid medications for chronic pain have been accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty about long-term effectiveness.
Human rights, drug control and the UN special prodedures
This publication examines human rights violations - such as arbitrary detention - occurring as a consequence of drug control or enforcement efforts to control the illicit trade and consumption of certain drugs.
This publication examines human rights violations - such as arbitrary detention - occurring as a consequence of drug control or enforcement efforts to control the illicit trade and consumption of certain drugs.
Trends in opioid analgesic abuse and mortality in the United States
The use of prescription opioid medications has increased greatly in the United States during the past two decades; in 2010, there were 16,651 opioid-related deaths.
The use of prescription opioid medications has increased greatly in the United States during the past two decades; in 2010, there were 16,651 opioid-related deaths.
Fact Sheet on the proposal to discuss international scheduling of ketamine at the 58th CND
Scheduling ketamine will leave most rural areas of developing countries with no alternative anaesthetics for essential surgery, and will further deepen the already acute crisis of global surgery.
Scheduling ketamine will leave most rural areas of developing countries with no alternative anaesthetics for essential surgery, and will further deepen the already acute crisis of global surgery.
Preventing fatal overdoses: A systematic review of the effectiveness of take-home naloxone
This paper considers how naloxone — an effective antidote that can reverse opioid intoxication — combined with training in first aid for coping with an overdose for people who are not health professionals can help save lives.
This paper considers how naloxone — an effective antidote that can reverse opioid intoxication — combined with training in first aid for coping with an overdose for people who are not health professionals can help save lives.
Do benzodiazepines increase the risk of dementia?
A Canadian case-control study published has reinforced previous concerns of a link between benzodiazepines and dementia, suggesting a more permanent impact.
A Canadian case-control study published has reinforced previous concerns of a link between benzodiazepines and dementia, suggesting a more permanent impact.
Pharmacological treatment of attention deficit hyperactivity disorder with co-morbid drug dependence
Drug dependence is frequent in patients with attention deficit hyperactivity disorder (ADHD). Nevertheless, the efficacy and safety of pharmacological treatments in this population are unclear.
Drug dependence is frequent in patients with attention deficit hyperactivity disorder (ADHD). Nevertheless, the efficacy and safety of pharmacological treatments in this population are unclear.
Is there a better way to treat substance use in adolescents with co-occurring mental health disorders?
The majority of adolescents entering substance use treatment also have psychiatric disorders, such as depression, ADHD and trauma-related problems. A new review proposes a combination of cognitive-behavioral and family therapies, may be an ideal treatment method for this patient population.
The majority of adolescents entering substance use treatment also have psychiatric disorders, such as depression, ADHD and trauma-related problems. A new review proposes a combination of cognitive-behavioral and family therapies, may be an ideal treatment method for this patient population.
Cooperation between drug law enforcement, health, and social services in South Eastern Europe
This study highlights five main consequences of the international drug control system, as well as opportunities for cooperation between law enforcement and health services.
This study highlights five main consequences of the international drug control system, as well as opportunities for cooperation between law enforcement and health services.
